Pharmacophore modeling and virtual screening for the discovery of new fatty acid amide hydrolase inhibitors
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چکیده
منابع مشابه
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Cannabis and analogs of Δ<sup>9</sup>-tetrahydrocannabinol have been used for therapeutic purposes, but their therapeutic use remains limited because of various adverse effects. Endogenous cannabinoids have been discovered, and dysregulation of endocannabinoid signaling is implicated in the pathophysiology of major depressive disorder (MDD). Recently, endocannabinoid hydrolytic enzy...
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ژورنال
عنوان ژورنال: Acta Pharmaceutica Sinica B
سال: 2011
ISSN: 2211-3835
DOI: 10.1016/j.apsb.2011.04.003